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KMID : 0379119820100010049
Korean Journal of Mycology
1982 Volume.10 No. 1 p.49 ~ p.50
Studies on the Constituents of the Higher Fungi of Korea (34)


Choi Eung-Chil


Abstract
To investigate the antitumor components of Korean higher fungi, the carpophores of Ramaria formosa (Fr.) Que¢¥l were collected in Gang Won Province and extracted with hot water.
The extracts were concentrated and precipitated by four volumes of enthanol. The precipitates were centrifugated and purified lay dialyzing through visking tube and polysaccharide fractions were obtained. The antitumor activity of the fraction was tested against Sarcoma 180 implanted in mice.
The tumor inhibition ratio of the polysaccharide fraction against the tumor was 66% in the dose of 50§·/§¸/day for the period of tert days. The tumor in two of the ten mice was completely regressed.
The components of these aqueous extracts were found to be polysaccharide and protein by color reactions including Anthrone and Lowry-Folin tests. The chemical analysis of the polysaccharide fraction was also undertaken.
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